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p107 anticorps (AA 751-850)

RBL1 Reactivité: Humain WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN755068
  • Antigène Voir toutes p107 (RBL1) Anticorps
    p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
    Épitope
    • 18
    • 14
    • 8
    • 8
    • 8
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 751-850
    Reactivité
    • 78
    • 19
    • 10
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 74
    • 4
    Lapin
    Clonalité
    • 75
    • 3
    Polyclonal
    Conjugué
    • 31
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp p107 est non-conjugé
    Application
    • 65
    • 37
    • 26
    • 26
    • 10
    • 9
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human p107/RBL1
    Isotype
    IgG
    Top Product
    Discover our top product RBL1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
    Autre désignation
    p107 (RBL1 Produits)
    Synonymes
    anticorps p107, anticorps prb1, anticorps fj58e06, anticorps wu:fj58e06, anticorps CP107, anticorps PRB1, anticorps AW547426, anticorps retinoblastoma-like 1 L homeolog, anticorps RB transcriptional corepressor like 1, anticorps retinoblastoma-like 1 (p107), anticorps retinoblastoma-like 1, anticorps rbl1.L, anticorps RBL1, anticorps rbl1, anticorps Rbl1
    Sujet

    Synonyms: 107 kDa retinoblastoma-associated protein, Cellular protein 107, Cellular protein p107, CP107, MGC40006, p107, PRB1, RBL1, RBL1_HUMAN, Retinoblastoma like protein 1, retinoblastoma-like 1 p107, Retinoblastoma-like protein 1.

    Background: p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.

    ID gène
    5933
    Pathways
    Cycle Cellulaire, Mitotic G1-G1/S Phases
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