CREM anticorps (AA 251-361)

N° du produit ABIN755362

Détail du produit anti-CREM anticorps

Antigène: CREM (CAMP Responsive Element Modulator (CREM))

Épitope: AA 251-361

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CREM est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris

Homologie: Rat,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CREM

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CREM

Antigène: CREM (CAMP Responsive Element Modulator (CREM))

Autre désignation: CREM (CREM Produits)

Synonymes: anticorps CREM, anticorps ICER, anticorps CREM-2, anticorps hCREM-2, anticorps ICERI, anticorps Icer, anticorps cAMP responsive element modulator, anticorps CREM, anticorps Crem

Sujet:

Synonyms: cAMP response element modulator, CREM-1, cAMP responsive element modulator, hCREM 2, hCREM2, ICER, Inducible cAMP early repressor, Inducible cAMP early repressor ICER, MGC111110, MGC17881, MGC41893.

Background: CREM is a a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is derived from a multiexonic gene that encodes both activators and antagonists of cAMP-inducible transcription by differential splicing. Splice variants with antagonistic function lack 2 glutamine-rich domains and block cAMP-induced transcription, whereas an isoform that includes these glutamine-rich domains is a transcriptional activator.

ID gène: 1390

UniProt: Q03060

Pathways: Retinoic Acid Receptor Signaling Pathway