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NCEH1 anticorps (AA 151-250)

NCEH1 Reactivité: Humain ELISA, IF (cc), IF (p), IHC (fro), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN755752
  • Antigène Voir toutes NCEH1 Anticorps
    NCEH1 (Neutral Cholesterol Ester Hydrolase 1 (NCEH1))
    Épitope
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    Reactivité
    • 21
    • 13
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 20
    • 1
    Lapin
    Clonalité
    • 21
    Polyclonal
    Conjugué
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NCEH1 est non-conjugé
    Application
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human,Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human AADACL1
    Isotype
    IgG
    Top Product
    Discover our top product NCEH1 Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    NCEH1 (Neutral Cholesterol Ester Hydrolase 1 (NCEH1))
    Autre désignation
    AADACL1 (NCEH1 Produits)
    Synonymes
    anticorps AADACL1, anticorps NCEH, anticorps Aadacl1, anticorps B230106I24Rik, anticorps CPO-BP, anticorps Nceh, anticorps RGD1311104, anticorps nceh, anticorps aadacl1, anticorps MGC79479, anticorps nceh1b, anticorps zgc:153038, anticorps zgc:92416, anticorps neutral cholesterol ester hydrolase 1, anticorps neutral cholesterol ester hydrolase 1 S homeolog, anticorps neutral cholesterol ester hydrolase 1b, tandem duplicate 1, anticorps neutral cholesterol ester hydrolase 1a, anticorps NCEH1, anticorps Nceh1, anticorps nceh1, anticorps nceh1.S, anticorps nceh1b.1, anticorps nceh1a
    Sujet

    Synonyms: Arylacetamide deacetylase like 1, Arylacetamide deacetylase-like 1, Kiaa1363, NCEH, Nceh1, NCEH1_HUMAN, Neutral cholesterol ester hydrolase 1, Neutral cholesterol ester hydrolase.

    Background: The assembly of very-low-density lipoproteins (VLDLs) in the secretory apparatus of the hepatocyte relies on the mobilization of triacylglycerol (TAG) from the cytosolic pool by lipolysis and re-esterification. However, some of the re-esterified TAG products are returned to the cytosolic pool in the liver, which protects vulnerable body tissues from excess lipotoxic non-esterified fatty acids in the plasma. Some of the lipases involved in this process include arylacetamide deacetylase (AADAC) and its related proteins AADACL1 and AADACL2. AADAC, a single pass type II membrane protein of the endoplasmic reticulum, is expressed in hepatocytes, intestinal mucosal cells, pancreas and adrenal gland. It plays an important role in the metabolic activation of arylamine substrates to ultimate carcinogens. AADACL1 hydrolyzes the metabolic intermediate 2-acetyl monoalkylglycerol, and its inactivation results in disruption of ether lipid metabolism in cancer cells and impaired cell migration and tumor growth.

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