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ADAMTSL2 anticorps (AA 522-580) (Cy5)

ADAMTSL2 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5
N° du produit ABIN758985
  • Antigène Voir toutes ADAMTSL2 Anticorps
    ADAMTSL2 (ADAMTS-Like 2 (ADAMTSL2))
    Épitope
    • 14
    • 1
    • 1
    • 1
    • 1
    AA 522-580
    Reactivité
    • 26
    • 3
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 25
    • 1
    Lapin
    Clonalité
    • 26
    Polyclonal
    Conjugué
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ADAMTSL2 est conjugé à/à la Cy5
    Application
    • 18
    • 12
    • 12
    • 6
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ADAMTSL2
    Isotype
    IgG
    Top Product
    Discover our top product ADAMTSL2 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ADAMTSL2 (ADAMTS-Like 2 (ADAMTSL2))
    Autre désignation
    ADAMTSL2 (ADAMTSL2 Produits)
    Synonymes
    anticorps ADAMTSL2, anticorps GPHYSD1, anticorps A930008K15Rik, anticorps tcp-1, anticorps RGD1305459, anticorps ADAMTS-like 2, anticorps ADAMTS like 2, anticorps ADAMTS-like protein 2, anticorps ADAMTSL2, anticorps adamtsl2, anticorps LOC100589493, anticorps Adamtsl2
    Sujet

    Synonyms: ADAMTS like 2, ADAMTS like protein 2, ADAMTS-like protein 2, ADAMTSL 2, ADAMTSL-2, ADAMTSL2, ATL2_HUMAN.

    Background: ADAMTS (A Disintegrin And Metalloproteinase Domain with Thrombospondin type 1 Modules) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions, including arthritis and cancer. ADAMTS protein family members contain an amino-terminal propeptide domain, a metalloproteinase domain, a disintegrin-like domain and a carboxy-terminus that contains a varying number of Thrombospondin type 1 (TSP-1) motifs. ADAMTS-L2 (ADAMTS-like protein 2) is a 951 amino acid secreted protein that is highly expressed in lung, kidney and liver. Mutations in the gene encoding ADAMTS are the cause of geleophysic dysplasia, an autosomal recessive disorder characterized by cardiac vavular anomalies, short stature, thick skin and brachydactyly. In individuals affected with geleophysic dysplasia, there is a significant increase in total active TGF-beta 1 and nuclear locations of p-SAMD2 in fibroblasts. Interestingly, ADAMTS-L2 interacts with LTBP-1, a glycoprotein that is part of the platelet-derived TGF-beta 1 complex.

    ID gène
    9719
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