Kallikrein 6 anticorps (AA 217-244)

N° du produit ABIN759101

Détail du produit anti-Kallikrein 6 anticorps

Antigène: Kallikrein 6 (KLK6)

Épitope: AA 217-244

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Rat

Homologie: Human,Mouse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KLK6

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Kallikrein 6

Antigène: Kallikrein 6 (KLK6)

Autre désignation: Klk6 (KLK6 Produits)

Synonymes: anticorps Bssp, anticorps Klk7, anticorps PRSS18, anticorps PRSS9, anticorps SP59, anticorps hK6, anticorps Prss9, anticorps AI849898, anticorps BSP, anticorps Klk29, anticorps MSP, anticorps Prss18, anticorps neurosin, anticorps kallikrein related peptidase 6, anticorps kallikrein related-peptidase 6, anticorps kallikrein-6, anticorps KLK6, anticorps Klk6, anticorps LOC100716801

Sujet:

Synonyms: hK6, Bssp, Klk7, SP59, PRSS9, PRSS18, Kallikrein-6, Neurosin, Protease M, Serine protease 18, Serine protease 9, Zyme, KLK6

Background: Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis.

ID gène: 5653

UniProt: Q92876

Pathways: Système du Complément, Regulation of G-Protein Coupled Receptor Protein Signaling