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P4HTM anticorps (AA 201-300)

P4HTM Reactivité: Humain WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN759521
  • Antigène Voir toutes P4HTM Anticorps
    P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))
    Épitope
    • 29
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 201-300
    Reactivité
    • 38
    • 25
    • 19
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 51
    • 2
    Lapin
    Clonalité
    • 53
    Polyclonal
    Conjugué
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp P4HTM est non-conjugé
    Application
    • 41
    • 25
    • 25
    • 10
    • 6
    • 5
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human HIFPH4
    Isotype
    IgG
    Top Product
    Discover our top product P4HTM Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))
    Autre désignation
    HPH4 (P4HTM Produits)
    Synonymes
    anticorps Ph-4, anticorps RGD1311848, anticorps EGLN4, anticorps HIFPH4, anticorps P4H-TM, anticorps PH-4, anticorps PH4, anticorps PHD4, anticorps 4933406E20Rik, anticorps AI853847, anticorps BB128974, anticorps prolyl 4-hydroxylase, transmembrane, anticorps prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum), anticorps shisa family member 5, anticorps P4htm, anticorps P4HTM, anticorps SHISA5
    Sujet

    Synonyms: EGLN4, H prolyl hydroxylase PH4, H-PH4, H-prolyl hydroxylase 4, HPH4, HPH-4, Hypoxia inducible factor prolyl 4 hydroxylase, Hypoxia inducible factor prolyl hydroxylase, Hypoxia-inducible factor prolyl hydroxylase 4, P4H TM, P4H with transmembrane domain, P4H-TM, P4htm, P4HTM_HUMAN, PH 4, PH4, PHD4, Proline 4 hydroxylase, Prolyl 4 hydroxylase transmembrane endoplasmic reticulum, Prolyl hydroxlase domain containing 4, Transmembrane prolyl 4-hydroxylase.

    Background: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

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