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PATZ1 anticorps (AA 351-450)

ZNF278 Reactivité: Humain WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN759836
  • Antigène Voir toutes PATZ1 (ZNF278) Anticorps
    PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))
    Épitope
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reactivité
    • 22
    • 16
    • 8
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 18
    • 4
    Lapin
    Clonalité
    • 20
    • 2
    Polyclonal
    Conjugué
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PATZ1 est non-conjugé
    Application
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PATZ1
    Isotype
    IgG
    Top Product
    Discover our top product ZNF278 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))
    Autre désignation
    PATZ1 (ZNF278 Produits)
    Synonymes
    anticorps ZNF278, anticorps MAZR, anticorps PATZ, anticorps RIAZ, anticorps ZBTB19, anticorps ZSG, anticorps dJ400N23, anticorps 8430401L15Rik, anticorps AI447519, anticorps Mazr, anticorps Patz, anticorps Zfp278, anticorps Znf278, anticorps POZ/BTB and AT hook containing zinc finger 1, anticorps POZ/BTB and AT hook containing zinc finger 1 S homeolog, anticorps POZ (BTB) and AT hook containing zinc finger 1, anticorps POZ-, AT hook-, and zinc finger-containing protein 1, anticorps PATZ1, anticorps patz1.S, anticorps Patz1, anticorps LOC100153931
    Sujet

    Synonyms: POZ-, AT hook-, and zinc finger-containing protein 1, BTB/POZ domain zinc finger transcription factor, Protein kinase A RI subunit alpha-associated protein, Zinc finger and BTB domain-containing protein 19, Zinc finger protein 278, Zinc finger sarcoma gene protein, PATZ1, PATZ, RIAZ, ZBTB19, ZNF278, ZSG

    Background: The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1,22)(p36.1,q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq, Jul 2008]

    ID gène
    23598
    UniProt
    Q9HBE1
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