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FGFRL1 anticorps (AA 231-330) (Biotin)

FGFRL1 Reactivité: Humain WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN761683
  • Antigène Voir toutes FGFRL1 Anticorps
    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
    Épitope
    • 14
    • 8
    • 8
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 231-330
    Reactivité
    • 51
    • 13
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 52
    • 1
    • 1
    Lapin
    Clonalité
    • 52
    • 2
    Polyclonal
    Conjugué
    • 20
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FGFRL1 est conjugé à/à la Biotin
    Application
    • 42
    • 21
    • 21
    • 13
    • 13
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human FGFR5/FGFRL1
    Isotype
    IgG
    Top Product
    Discover our top product FGFRL1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
    Autre désignation
    FGFR5 (FGFRL1 Produits)
    Synonymes
    anticorps fgfrl1, anticorps zgc:64084, anticorps FGFR5, anticorps FGFR5beta, anticorps FGFR5gamma, anticorps Fgfr5, anticorps FHFR, anticorps XFGFRL1, anticorps Xndk, anticorps fgfrl1-a, anticorps fgfrl1-b, anticorps ndk, anticorps im:7154242, anticorps fibroblast growth factor receptor like 1a, anticorps fibroblast growth factor receptor-like 1, anticorps fibroblast growth factor receptor like 1, anticorps fibroblast growth factor receptor like 1 L homeolog, anticorps fibroblast growth factor receptor like 1b, anticorps fgfrl1a, anticorps Fgfrl1, anticorps FGFRL1, anticorps fgfrl1.L, anticorps fgfrl1b
    Sujet

    Synonyms: FGF homologous factor receptor, FGF receptor like protein 1, FGFR 5, FGFR like protein, FGFR5, FGFRL1, FHFR, Fibroblast growth factor receptor 5, Fibroblast growth factor receptor like 1, FGRL1_HUMAN.

    Background: FGFRL1 is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between FGFRL1 and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found.

    ID gène
    53834
    Pathways
    Signalisation RTK
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