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Nicastrin anticorps (AA 21-120)

NCSTN Reactivité: Souris WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN761801
  • Antigène Voir toutes Nicastrin (NCSTN) Anticorps
    Nicastrin (NCSTN)
    Épitope
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reactivité
    • 37
    • 32
    • 22
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 49
    • 3
    Lapin
    Clonalité
    • 42
    • 10
    Polyclonal
    Conjugué
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Nicastrin est non-conjugé
    Application
    • 38
    • 12
    • 12
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat,Cow,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Nicastrin
    Isotype
    IgG
    Top Product
    Discover our top product NCSTN Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Ku, Li, Gao, Zhang, Yan, Ji, Li, Sang: "NF-κB-regulated microRNA-574-5p underlies synaptic and cognitive impairment in response to atmospheric PM2.5 aspiration." dans: Particle and fibre toxicology, Vol. 14, Issue 1, pp. 34, (2018) (PubMed).

  • Antigène
    Nicastrin (NCSTN)
    Autre désignation
    Nicastrin (NCSTN Produits)
    Synonymes
    anticorps CG7012, anticorps Dmel\\CG7012, anticorps Nct, anticorps Nic, anticorps S5A, anticorps ST96B, anticorps agro, anticorps dNct, anticorps nic, anticorps NCSTN, anticorps DKFZp469O2418, anticorps APH2, anticorps 9430068N19Rik, anticorps AA727311, anticorps Aph2, anticorps D1Dau13e, anticorps Kiaa0253, anticorps mKIAA0253, anticorps nicastrin, anticorps Nicastrin, anticorps NCSTN, anticorps nct, anticorps ncstn, anticorps CpipJ_CPIJ001617, anticorps Ncstn, anticorps aph-2
    Sujet

    Synonyms: ATAG1874, Nicastrin, NCSTN, KIAA0253, UNQ1874/PRO4317

    Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

    ID gène
    23385
    UniProt
    Q92542
    Pathways
    Signalisation Notch, Neurotrophin Signaling Pathway
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