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RND3 anticorps (AA 51-150)

RND3 Reactivité: Humain, Rat ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN762356
  • Antigène Voir toutes RND3 Anticorps
    RND3 (rho Family GTPase 3 (RND3))
    Épitope
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivité
    • 30
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Rat
    Hôte
    • 16
    • 14
    Lapin
    Clonalité
    • 16
    • 14
    Polyclonal
    Conjugué
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RND3 est non-conjugé
    Application
    • 16
    • 13
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Rat
    Homologie
    Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human RND3
    Isotype
    IgG
    Top Product
    Discover our top product RND3 Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    RND3 (rho Family GTPase 3 (RND3))
    Autre désignation
    Rnd3 (RND3 Produits)
    Synonymes
    anticorps ARHE, anticorps Rho8, anticorps RhoE, anticorps memB, anticorps MGC83857, anticorps 2610017M01Rik, anticorps AI661404, anticorps Arhe, anticorps Rhoe, anticorps RHOE, anticorps arhe, anticorps id:ibd2712, anticorps id:ibd2919, anticorps rho8, anticorps rnd3, anticorps wu:fc39h07, anticorps zgc:73080, anticorps wu:fd06e12, anticorps zgc:92324, anticorps Rho family GTPase 3, anticorps Rho family GTPase 3 L homeolog, anticorps Rho family GTPase 3a, anticorps Rho family GTPase 3b, anticorps RND3, anticorps rnd3.L, anticorps Rnd3, anticorps rnd3a, anticorps rnd3b
    Sujet

    Synonyms: ARHE, memB, Rho family GTPase 3, Rho8, RhoE, RND3_HUMAN.

    Background: The Rho family of proteins mediates cytoskeleton organization and cell motility responses. This family contains twenty different members divided into five groups, the Rho-like, Rac-like, Cdc42-like, Rnd and RhoBTB subfamilies. Rho proteins have GTPase activity and bind GTP in their active form and GDP in their inactive form. In their active form they interact with downstream proteins. However, the Rnd subfamily of proteins containing the Rnd1, Rnd2 and RhoE(Rnd3), binds GTP but not GDP and has no GTPase activity. While Rho proteins are required for stress fibre formation in cultured fibroblasts, epithelial and endothelial cells, overexpression of Rnd3 or Rnd1 in the same cells may cause an opposite effect (i.e. decrease in stress fibre). Thus, the Rnd3 protein may act as an antagonist for the Rho proteins either by directly binding to Rho or to other downstream proteins.

    ID gène
    390
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