RNF139 anticorps (AA 501-600) (Biotin)

N° du produit ABIN762373

Détail du produit anti-RNF139 anticorps (Biotin)

Antigène: RNF139 (Ring Finger Protein 139 (RNF139))

Épitope: AA 501-600

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF139 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RNF139

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur RNF139

Antigène: RNF139 (Ring Finger Protein 139 (RNF139))

Autre désignation: RNF139 (RNF139 Produits)

Synonymes: anticorps HRCA1, anticorps RCA1, anticorps TRC8, anticorps 4930555P18Rik, anticorps zgc:175173, anticorps rnf139, anticorps ring finger protein 139, anticorps ring finger protein 139 S homeolog, anticorps RNF139, anticorps Rnf139, anticorps rnf139, anticorps rnf139.S

Sujet:

Synonyms: HRCA1, RCA1, Ring finger protein 139, TRC8, RN139_HUMAN.

Background: The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.

ID gène: 11236