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CD83 anticorps

CD83 Reactivité: Humain, Non-Human Primate FACS, IHC (fro) Hôte: Souris Monoclonal HB15e unconjugated
N° du produit ABIN775709
  • Antigène Voir toutes CD83 Anticorps
    CD83
    Reactivité
    • 78
    • 54
    • 24
    • 3
    • 2
    • 1
    Humain, Non-Human Primate
    Hôte
    • 60
    • 27
    • 16
    • 1
    Souris
    Clonalité
    • 62
    • 39
    • 1
    Monoclonal
    Conjugué
    • 35
    • 8
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD83 est non-conjugé
    Application
    • 57
    • 53
    • 18
    • 14
    • 10
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    The mouse monoclonal antibody HB15e recognizes an extracellular epitope of CD83, a 40-45 kDa type I glycoprotein expressed on mature dendritic cells.
    Réactivité croisée (Details)
    Human, Non-Human Primates
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    Human CD83-transfected Cos cells
    Clone
    HB15e
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD83 Anticorps primaire
  • Indications d'application
    Flow cytometry:Recommended dilution: 1-4 μg/mL, Positive control: peripheral blood-derived dendritic cells.
    Immunohistochemistry (frozen sections): acetone fixation.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Antigène
    CD83
    Autre désignation
    CD83 (CD83 Produits)
    Synonymes
    anticorps BL11, anticorps HB15, anticorps CD83 molecule, anticorps CD83 antigen, anticorps Cd83, anticorps CD83
    Sujet
    CD83 Molecule,CD83 is a 40-45 kDa heavily glycosylated type I cell surface glycoprotein of immunoglobulin family. It is expressed on the surface of mature dendritic cells, Langerhans cells in the skin, and interdigitating reticulum cells in the lymphoid tissues. Low expression of CD83 has been reported in activated T and B cells. Cytoplasmic expression of CD83 can be detected also in monocytes and macrophages. CD83 is involved in modulation of antigen presentation. Soluble CD83 has immunoregulatory functions, it is able to down-regulate dendritic cell maturation and stimulation of T cells. In the developing immune system, release of soluble CD83 from dendritic cells upon stimulation by gram-positive or gram-negative bacteria has anti-allergic effect. Herpes simplex virus, on the other hand, causes CD83 degradation in mature dendritic cells.,BL11, HB15
    ID gène
    9308
    UniProt
    Q01151
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