Monoclonal antibody 5ST-4A9 recognizes Human Stromelysin-3. SL-3 (MMP-11) was originally isolated as a breast cancer associated gene. Antigen Distribution: Specifically expressed in stromal cells of breast carcinomas.
Purification
Affinity Chromatography
Immunogène
Full length recombinant Human Stromelysin-3. Antigen, epitope: The epitope has not been further characterized.
The MMP stromelysin-3 shares many similarities with other MMPs but also has several unique properties. It has little expression in adult organs under normal physiological conditions but is upregulated in a number of pathological processes such as tumor invasion and may also be involved in tumor initiation. During mammalian development, ST3 is expressed in many processes involving cell migration and tissue morphogenesis, especially where cell death takes place.Synonyms: MMP11, Matrix metalloproteinase-11, SL-3, ST3, STMY3, Stromelysin-3