RND3 anticorps (AA 1-245)

N° du produit ABIN782334

Détail du produit anti-RND3 anticorps

Antigène: RND3 (rho Family GTPase 3 (RND3))

Épitope: AA 1-245

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RND3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: Recognizes RND3 / ARHE.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Protein A Chromatography

Immunogène: RND3 antibody was raised against RND3 (AAH12513, 1 a.a. ~ 245 a.a) full-length recombinant protein with GST tag.

Clone: 1D2

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C or -80 °C.

Détails sur RND3

Antigène: RND3 (rho Family GTPase 3 (RND3))

Autre désignation: RND3 / ARHE (RND3 Produits)

Synonymes: anticorps ARHE, anticorps Rho8, anticorps RhoE, anticorps memB, anticorps MGC83857, anticorps 2610017M01Rik, anticorps AI661404, anticorps Arhe, anticorps Rhoe, anticorps RHOE, anticorps arhe, anticorps id:ibd2712, anticorps id:ibd2919, anticorps rho8, anticorps rnd3, anticorps wu:fc39h07, anticorps zgc:73080, anticorps wu:fd06e12, anticorps zgc:92324, anticorps Rho family GTPase 3, anticorps Rho family GTPase 3 L homeolog, anticorps Rho family GTPase 3a, anticorps Rho family GTPase 3b, anticorps RND3, anticorps rnd3.L, anticorps Rnd3, anticorps rnd3a, anticorps rnd3b

Sujet: Rho-related GTP-binding protein RhoE, also known as RND3, is a small GTPase of the Ras superfamily that regulate the organization of the actin cytoskeleton in response to extracellular growth factors. RND3 activity leads to a decrease in stress fibers and increased cell migration, at least in part through regulation of the Rho-dependent kinase ROCK1. Also, RND3 has been implicated in inhibition of DNA-damage induced apoptosis and cell cycle arrest.Synonyms: MemB protein, RHO8, RHOE, Rho family GTPase 3, Rho-related GTP-binding protein RhoE

ID gène: 390

NCBI Accession: NP_005159

UniProt: P61587