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TNF alpha anticorps (AA 1-234)
TNF alpha
Reactivité: Humain, Rat
WB, IHC (p), EIA
Hôte: Souris
Monoclonal
M1-C4
unconjugated
Détail du produit anti-TNF alpha anticorps
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Antigène
Voir toutes TNF alpha Anticorps
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Épitope
Tous les épitopes à travers TNF alpha Anticorps.
AA 1-234
Reactivité
Toutes les réactivités sur TNF alpha Anticorps
Humain, Rat
Hôte
Toutes les hôtes sur TNF alpha Anticorps
Souris
Clonalité
Toutes les clonalités sur TNF alpha Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers TNF alpha Anticorps
Cet anticorp TNF alpha est non-conjugé
Application
Tous les applications à travers TNF alpha Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificité
This antibody reacts to TNF.
Purification
Affinity chromatography on Protein A
Immunogène
TNF antibody was raised against tNF (AAH28148, 1 a.a. ~ 234 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Clone
M1-C4
Isotype
IgG1
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0,5 mg/mL
Buffer
PBS, pH 7.2
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur TNF alpha
(cache)
Antigène
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Autre désignation
Tumor Necrosis Factor (TNF-Alpha) (TNF alpha Produits )
Synonymes
anticorps DIF, anticorps TNF-alpha, anticorps TNFA, anticorps TNFSF2, anticorps RATTNF, anticorps Tnfa, anticorps tnf, anticorps TNF-a, anticorps TNFalpha, anticorps Tnfsf1a, anticorps TNFa, anticorps cTNF, anticorps Tnf-alpha, anticorps tnfa-like, anticorps TNF-ALPHA, anticorps dif, anticorps tnfa, anticorps xtnf, anticorps tnfsf2, anticorps tnf-alpha, anticorps Cachectin, anticorps tumor necrosis factor, anticorps tumor necrosis factor b (TNF superfamily, member 2), anticorps tumor necrosis factor alpha, anticorps tumor necrosis factor a (TNF superfamily, member 2), anticorps TNF, anticorps Tnf, anticorps tnf, anticorps tnfb, anticorps tnf-alpha, anticorps LOC103694380, anticorps tnfa
Sujet
Tumor Necrosis Factor (TNF) is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. TNF is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.Synonyms: Cachectin, TNF, TNF-a, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2
ID gène
7124
NCBI Accession
NP_000585
UniProt
P01375
Pathways
Signalisation NF-kappaB , Apoptose , Caspase Cascade in Apoptosis , Signalisation TLR , Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Positive Regulation of Endopeptidase Activity , Hepatitis C , Protein targeting to Nucleus , Inflammasome
Vus récemment
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