GSTA1 anticorps (AA 1-222)

N° du produit ABIN782405

Détail du produit anti-GSTA1 anticorps

Antigène: GSTA1 (Glutathione S-Transferase alpha 1 (GSTA1))

Épitope: AA 1-222

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GSTA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to GSTA1.

Purification: Affinity chromatography on Protein A

Immunogène: GSTA1 antibody was raised against gSTA1 (AAH53578.1, 1 a.a. ~ 222 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2F7

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: PBS, pH 7.2

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C to -80 °C.

Détails sur GSTA1

Antigène: GSTA1 (Glutathione S-Transferase alpha 1 (GSTA1))

Autre désignation: GSTA1 (GSTA1 Produits)

Synonymes: anticorps GST2, anticorps GSTA1-1, anticorps GTH1, anticorps Gst2-1, anticorps OTTMUSG00000031890, anticorps GSTA3, anticorps GST, anticorps GSTA1, anticorps gst2, anticorps gth1, anticorps gsta1-1, anticorps Gsta1, anticorps Gst-2, anticorps Gst-3, anticorps Gst2, anticorps Gst3, anticorps glutathione S-transferase alpha 1, anticorps glutathione S-transferase, alpha 1 (Ya), anticorps glutathione S-transferase alpha 3, anticorps glutathione S-transferase alpha 5, anticorps glutathione S-transferase alpha 1 L homeolog, anticorps glutathione S-transferase alpha 2, anticorps glutathione S-transferase mu 2 (muscle), anticorps Glutathione S-transferase 2, anticorps glutathione S-transferase A, anticorps glutathione S-transferase Gst2, anticorps glutathione S-transferase 2, anticorps GSTA1, anticorps Gsta1, anticorps GSTA3, anticorps GSTA5, anticorps gsta1.L, anticorps gsta1, anticorps Gsta2, anticorps GSTM2, anticorps gst-2, anticorps LOC100713029, anticorps gst2, anticorps LOC101897277

Sujet: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.Synonyms: GST class-alpha member 1, GST-epsilon, GSTA1-1, GTH1, Glutathione S-transferase A1, HA subunit 1

ID gène: 2938

NCBI Accession: NP_665683

UniProt: P08263