Klotho anticorps (Center)
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- Antigène Voir toutes Klotho (KL) Anticorps
- Klotho (KL)
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Épitope
- Center
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Klotho est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunofluorescence (IF)
- Specificité
- This antibody detects Klotho at center.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- 16 amino acid peptide near the center of human KLOTHO
- Top Product
- Discover our top product KL Anticorps primaire
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anti-Klotho (KL) (AA 516-955) antibody
KL Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Klotho (KL) (AA 401-500) antibodyKL Reactivité: Humain, Souris, Rat IHC (p), IHC (fro), IF (p) Hôte: Lapin Polyclonal unconjugated
anti-Klotho (KL) (AA 517-956) antibodyKL Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Klotho (KL) (AA 986-1012), (C-Term) antibodyKL Reactivité: Humain WB, FACS Hôte: Lapin Polyclonal RB21226 unconjugated
anti-Klotho (KL) (AA 720-769) antibodyKL Reactivité: Humain, Rat, Lapin, Boeuf (Vache), Chien, Porc, Singe IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Klotho (KL) (AA 251-300) antibodyKL Reactivité: Humain, Souris, Rat, Lapin, Cheval, Chien, Cobaye, Roussette (Chauve-souris), Singe WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Klotho (KL) (Middle Region) antibodyKL Reactivité: Humain, Souris, Rat, Lapin, Cheval, Boeuf (Vache), Chien, Cobaye, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Klotho (KL) (Middle Region) antibodyKL Reactivité: Humain, Souris, Rat, Lapin, Cheval, Boeuf (Vache), Chien, Cobaye WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Klotho (KL) (N-Term) antibodyKL Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Klotho (KL) (AA 765-981) antibodyKL Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- Antigène
- Klotho (KL)
- Autre désignation
- Klotho (KL Produits)
- Synonymes
- anticorps alpha-kl, anticorps KL, anticorps LOC100223456, anticorps klotho, anticorps Klotho, anticorps KL, anticorps Kl, anticorps kl, anticorps LOC100533542
- Sujet
- KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling. KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor. Three isoforms of KLOTHO are known to exist.Synonyms: EC 3.2.1.31, KL, Klotho
- ID gène
- 9365
- NCBI Accession
- NP_004786
- UniProt
- Q9UEF7
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Activity, Growth Factor Binding
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