This antibody detects CTNNBL1 at C-term. CTNNBL1 antibody is predicted to not cross-react with other catenin family members. At least four isoforms of CTNNBL1 are known to exist, this antibody will detect all but isoform b.
Réactivité croisée (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Affinity chromatography purified via peptide column
Immunogène
20 amino acid peptide near the carboxy terminus of human CTTNBL1
anticorps ctnnbl1, anticorps MGC76112, anticorps MGC82423, anticorps PDGFRA, anticorps MGC84931, anticorps C20orf33, anticorps NAP, anticorps P14L, anticorps PP8304, anticorps dJ633O20.1, anticorps 5730471K09Rik, anticorps NYD-SP19, anticorps catenin beta like 1, anticorps catenin beta like 1 S homeolog, anticorps catenin beta like 1 L homeolog, anticorps catenin, beta like 1, anticorps ctnnbl1, anticorps CTNNBL1, anticorps ctnnbl1.S, anticorps ctnnbl1.L, anticorps Ctnnbl1
Sujet
The Beta-catenin-like protein 1 (CTNNBL1) contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs, as well as Armadillo/beta-catenin-like repeats. Transient expression of CTNNBL1 resulted in translocation to the nucleus and apoptosis, suggesting it may be involved in the apoptotic pathway. CTNNBL1 interacts with the Prp19 complex of the spliceosome and the Ig class switching enzyme activation-induced deaminase (AID) and had been suggested to play a role in antibody-diversification and class switching, but recent studies have shown CTNNBL1 to be dispensable for Ig class switch recombination. Other studies have identified CTTNBL1 as a novel gene for obesity.Synonyms: Beta-catenin-like protein 1, C20orf33, NYD-SP19, Nuclear-associated protein, Testis development protein NYD-SP19