MYZAP anticorps (C-Term)

N° du produit ABIN783419

Détail du produit anti-MYZAP anticorps

Antigène: MYZAP (Myocardial Zonula Adherens Protein (MYZAP))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYZAP est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects MYOZAP at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid peptide near the carboxy terminus of human MYOZAP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur MYZAP

Antigène: MYZAP (Myocardial Zonula Adherens Protein (MYZAP))

Autre désignation: MYOZAP (MYZAP Produits)

Synonymes: anticorps AA407270, anticorps AV006038, anticorps Gcom1, anticorps Gm640, anticorps Grinl1a7, anticorps Myozap, anticorps Myzap, anticorps GLURR2, anticorps GRINL1B, anticorps GCOM1, anticorps Gup, anticorps Gup1, anticorps Gup2, anticorps MYOZAP, anticorps myocardial zonula adherens protein, anticorps GRINL1B complex locus 2 (pseudogene), anticorps Myzap, anticorps GCOM2, anticorps MYZAP

Sujet: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein . It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.Synonyms: GCOM1, GRINL1A, Gup, Gup1, Myocardium-enriched zonula occludens-1-interacting protein, glutamate receptor ionotropic N-methyl D-aspartate-like 1A

ID gène: 145781

NCBI Accession: NP_001018100

UniProt: P0CAP1