ZNF219 anticorps (N-Term)

N° du produit ABIN783427

Détail du produit anti-ZNF219 anticorps

Antigène: ZNF219 (Zinc Finger Protein 219 (ZNF219))

Épitope: N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF219 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects ZNF219 at N-term. At least two isoforms of ZFP219 are known to exist, this antibody will recognize both.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid peptide near the amino terminus of human ZFP219

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur ZNF219

Antigène: ZNF219 (Zinc Finger Protein 219 (ZNF219))

Autre désignation: ZNF219 (ZNF219 Produits)

Synonymes: anticorps ZNF219, anticorps ZFP219, anticorps Znf219, anticorps 2010302A17Rik, anticorps zinc finger protein 219, anticorps ZNF219, anticorps Zfp219

Sujet: ZFP219 is a developmentally regulated member of the Kruppel-like zinc finger gene family that is thought to function as a transcriptional repressor. Yeast two-hybrid screening showed association with Sox9, a transcription factor that is essential for chondrogenesis. ZFP219 is specifically expressed in the developing limb buds and colocalizes with Sox9 in the nucleus. Knockdown of ZFP219 expression decreased Sox9-induced mRNA expression, and a dominant-negative mutant of ZFP219 inhibited Bmp2-induced chondrocyte differentiation, suggesting that ZFP219 plays an important role as a transcriptional partner of Sox9 in the regulation of chondrocyte differentiation.Synonyms: Zinc finger protein 219

ID gène: 51222

NCBI Accession: NP_001095142

UniProt: Q9P2Y4