LY9 anticorps (C-Term)
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- Antigène Voir toutes LY9 (CD229) Anticorps
- LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
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Épitope
- C-Term
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LY9 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects CD229 / LY9 at C-term. At least three isoforms of SLAMF3 are known to exist. This antibody is predicted to not cross-react with other protein family members.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- 18 amino acid peptide near the carboxy terminus of human CD229
- Top Product
- Discover our top product CD229 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- Antigène
- LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
- Autre désignation
- CD229 / LY9 (CD229 Produits)
- Synonymes
- anticorps LY9, anticorps CD229, anticorps SLAMF3, anticorps hly9, anticorps mLY9, anticorps AI893573, anticorps Lgp100, anticorps Ly-9, anticorps T100, anticorps lymphocyte antigen 9, anticorps LY9, anticorps Ly9
- Sujet
- The signaling lymphocyte-activation molecule family member 3 (SLAMF3), also known as LY9 and CD229, is a cell surface receptor that is expressed on T and B lymphocytes and belongs to the CD150/SLAMF1 receptor family. SLAMF3 was identified through a yeast two-hybrid screening in which SLAMF3 bound to the X-linked lymphoproliferative disease gene product SAP, suggesting that in activated T cells, SLAMF3 signaling can be triggered SAP. Its expression on the cell surface appears to be regulated via its interaction with the clathrin-associated adaptor complex 2 (AP-2). Despite its similarity to SLAMF1 in structure and interactions with SAP, SLAMF3-deficient mice do not exhibit phenotypic characteristics associated with SLAMF1- and SAP-deficient mice, suggesting that SLAMF3 plays other roles in T cell activation.Synonyms: Ly-9, Lymphocyte antigen 9, T-lymphocyte surface antigen Ly-9
- ID gène
- 4063
- NCBI Accession
- NP_002339
- UniProt
- Q9HBG7
- Pathways
- BCR Signaling
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