SIK2 anticorps (Center)
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- Antigène Voir toutes SIK2 Anticorps
- SIK2 (Salt-Inducible Kinase 2 (SIK2))
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Épitope
- Center
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SIK2 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects SIK2 at Center. SIK2 antibody is predicted to not cross-react with other SIK protein family members.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- 16 amino acid peptide near the center of human SIK2
- Top Product
- Discover our top product SIK2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- Antigène
- SIK2 (Salt-Inducible Kinase 2 (SIK2))
- Autre désignation
- SIK2 (SIK2 Produits)
- Synonymes
- anticorps PIG33, anticorps SC1, anticorps LOH11CR1I, anticorps QIK, anticorps SNF1LK2, anticorps G630080D20Rik, anticorps Snf1lk2, anticorps RGD1559698, anticorps si:dkey-27p23.1, anticorps snf1lk2a, anticorps SPARC like 1, anticorps salt inducible kinase 2, anticorps salt-inducible kinase 2, anticorps salt-inducible kinase 2a, anticorps SPARCL1, anticorps SIK2, anticorps SLK2, anticorps Sik2, anticorps sik2a
- Sujet
- Salt-inducible kinase 2 (SIK2), like its closely related homolog SIK1, belongs AMPK subfamily of the Ser/Thr protein kinase family and negatively regulates CRE-binding protein (CREB) activity by phosphorylating the CREB-specific coactivator transducer of regulated CREB activity (TORC). SIK2 is thought to be part of a signaling cascade that regulates the expression and activity of the insulin-induced genes PGC-1?alpha and UCP-1 in brown adipocytes, impairment of which has been implicated in obesity and insulin resistance in human and animal models. SIK2 has also been reported as a key regulator for neuronal survival after ischemia, suppressing CREB-mediated gene expression after oxygen-glucose deprivation.Synonyms: QIK, Qin-induced kinase, SIK-2, SNF1LK2, Salt-inducible protein kinase 2, Serine/threonine-protein kinase SIK2, Serine/threonine-protein kinase SNF1-like kinase 2
- ID gène
- 23235
- NCBI Accession
- NP_056006
- UniProt
- Q9H0K1
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