KAL1 anticorps (Center)
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- Antigène Voir toutes KAL1 Anticorps
- KAL1 (Kallmann Syndrome 1 Sequence (KAL1))
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Épitope
- Center
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KAL1 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects Anosmin (Center).
- Réactivité croisée (Details)
- Species reactivity (tested):Human
- Purification
- Affinity chromatography
- Immunogène
- Raised against an 18 amino acid peptide near the center of human Anosmin
- Top Product
- Discover our top product KAL1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- KAL1 (Kallmann Syndrome 1 Sequence (KAL1))
- Autre désignation
- Anosmin-1 (KAL1 Produits)
- Synonymes
- anticorps ADMLX, anticorps HH1, anticorps HHA, anticorps KAL, anticorps KALIG-1, anticorps KMS, anticorps WFDC19, anticorps KAL1, anticorps hha, anticorps kal, anticorps kms, anticorps admlx, anticorps kalig-1, anticorps anosmin-1a, anticorps kal1.1, anticorps kal1a, anticorps wu:fl91z45, anticorps anosmin 1, anticorps anosmin 1a, anticorps ANOS1, anticorps anos1, anticorps anos1a
- Sujet
- Mutations in Anosmin-1, an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron. Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.Synonyms: ADMLX, Adhesion molecule-like X-linked, KAL, KAL1, KALIG1, Kallmann syndrome protein
- ID gène
- 3730
- NCBI Accession
- NP_000207
- UniProt
- P23352
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