CMYA5 anticorps (C-Term)

N° du produit ABIN783522

Détail du produit anti-CMYA5 anticorps

Antigène: CMYA5 (Cardiomyopathy Associated 5 (CMYA5))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CMYA5 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Myospryn at C-term. SPRYD2 antibody is predicted to not cross-react with other SPRYD protein family members. At least four isoforms of SPRYD2 are known to exist.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat.

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid peptide near the carboxy terminus of human SPRYD2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur CMYA5

Antigène: CMYA5 (Cardiomyopathy Associated 5 (CMYA5))

Autre désignation: Myospryn (CMYA5 Produits)

Synonymes: anticorps cmya5l, anticorps DKFZp469P2126, anticorps C5orf10, anticorps SPRYD2, anticorps TRIM76, anticorps 2310076E16Rik, anticorps 2310076E21Rik, anticorps AA420382, anticorps AI504003, anticorps Srfsd, anticorps Tims, anticorps sr553, anticorps cardiomyopathy associated 5, anticorps CMYA5, anticorps cmya5, anticorps Cmya5

Sujet: SPRYD2, also known as Myospryn, was originally identified as the muscle-specific partner of dysbindin and as a Mef-2 target gene. It is a large scaffolding protein localized to the Z-disc/costamere region of striated muscle. SPRYD2 includes a noncanonical tripartite motif (TRIM-like) that lacks the RING domain but consists of a B-box coiled coil (BBC), fibronectin 3 (FN3) repeats, and SPRY domains. SPRYD2 interacts with desmin and calcineurin, and it has been suggested to play a role in the biogenesis of lysosome and negatively regulates slow-fiber-type transformation and skeletal muscle regeneration. SPRYD2 is dysregulated in Duchenne muscular dystrophy.Synonyms: C5orf10, CMYA5, Cardiomyopathy-associated protein 5, DTNBP2, Dystrobrevin-binding protein 2, Genethonin-3, SPRY domain-containing protein 2, SPRYD2, TRIM76, Tripartite motif-containing protein 76

ID gène: 202333

NCBI Accession: NP_705838

UniProt: Q8N3K9