This antibody recognizes Human SPTLC2. At least three isoforms of SPT2 are known to exist, this antibody will not detect isoform b. SPT2 antibody is predicted to not cross-react with SPT1.
anticorps HSN1C, anticorps LCB2, anticorps LCB2A, anticorps NSAN1C, anticorps SPT2, anticorps hLCB2a, anticorps sptlc2, anticorps zgc:110661, anticorps AI173915, anticorps mKIAA0526, anticorps Pomt2, anticorps LCB2a, anticorps SPTLC2, anticorps serine palmitoyltransferase long chain base subunit 2, anticorps serine palmitoyltransferase 2, anticorps serine palmitoyltransferase, long chain base subunit 2 S homeolog, anticorps serine palmitoyltransferase, long chain base subunit 2a, anticorps serine palmitoyltransferase, long chain base subunit 2, anticorps SPTLC2, anticorps LOC100446763, anticorps sptlc2, anticorps sptlc2.S, anticorps sptlc2a, anticorps Sptlc2
Sujet
SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.Synonyms: KIAA0526, LCB 2, LCB2, LCB2a, Long chain base biosynthesis protein 2, SPT 2, SPT2, Serine palmitoyltransferase 2, Serine-palmitoyl-CoA transferase 2