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SP110 anticorps (C-Term)

SP110 Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN783558
  • Antigène Voir toutes SP110 Anticorps
    SP110 (SP110 Nuclear Body Protein (SP110))
    Épitope
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 21
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 15
    • 6
    Lapin
    Clonalité
    • 18
    • 3
    Polyclonal
    Conjugué
    • 18
    • 1
    • 1
    • 1
    Cet anticorp SP110 est non-conjugé
    Application
    • 18
    • 9
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects SP110 at C-term.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    15 amino acid peptide near the carboxy terminus of the human IPR1
    Top Product
    Discover our top product SP110 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Antigène
    SP110 (SP110 Nuclear Body Protein (SP110))
    Autre désignation
    SP110 (SP110 Produits)
    Synonymes
    anticorps SP110, anticorps IFI41, anticorps IFI75, anticorps IPR1, anticorps VODI, anticorps 5031415C07Rik, anticorps 52kDa, anticorps 5830484A20Rik, anticorps ENSMUSG00000075603, anticorps Ifi75, anticorps Ipr1, anticorps SP110 nuclear body protein, anticorps Sp110 nuclear body protein, anticorps SP110, anticorps Sp110
    Sujet
    Susceptibility to tuberculosis (TB) in mice has recently been attributed to the IPR1 gene. IPR1 is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. SP110 is the closest homolog of the IPR1 protein in humans. The IPR1/Sp110 gene product might play a role in integrating signals generated by intracellular pathogens with mechanisms controlling innate immunity, cell death, and pathogenesis. IPR1/Sp110 is up-regulated after infection with M. tuberculosis and required by Anaplasma phagocytophilum for infection of human promyelocytic cells. Defects in Sp110 are a cause of severely impaired resistance to infection by M. tuberculosis.Synonyms: FLJ22835, IPR1, SP-110, SP110 nuclear body protein, Speckled 110 kD, VODI
    ID gène
    3431
    NCBI Accession
    NP_001171944
    UniProt
    Q9HB58
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