CDC42 anticorps (N-Term)
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- Antigène Voir toutes CDC42 Anticorps
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
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Poulet
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDC42 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects CDC42 at N-term.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- 17 amino acid peptide near the amino terminus of human CDC42
- Top Product
- Discover our top product CDC42 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- Antigène
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
- Autre désignation
- CDC42 (CDC42 Produits)
- Synonymes
- anticorps CDC42Hs, anticorps G25K, anticorps AI747189, anticorps AU018915, anticorps cdc42a, anticorps wu:fb07d08, anticorps wu:fj62g06, anticorps zgc:63918, anticorps Xcdc42, anticorps cdc42hs, anticorps g25k, anticorps CDC42, anticorps CG12530, anticorps Cdc42Dm, anticorps D-CDC42, anticorps D-Cdc42, anticorps D-cdc42, anticorps DCDC42, anticorps DCdc42, anticorps Dcdc42, anticorps Dm Cdc42, anticorps DmCDC42, anticorps Dmcdc42, anticorps Dmel\\CG12530, anticorps cdc42, anticorps cell division cycle 42, anticorps Cell division control protein 42 homolog, anticorps cell division control protein 42 homolog, anticorps cell division cycle 42 L homeolog, anticorps CG12530 gene product from transcript CG12530-RC, anticorps Rho family GTPase, anticorps CDC42, anticorps Cdc42, anticorps cdc42, anticorps LOC100636735, anticorps LOC100637699, anticorps LOC100638834, anticorps cdc42.L
- Sujet
- CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to S. cerevisiae CDC42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. CDC42 is thought to regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. At least two isoforms of CDC42 are known to exist.Synonyms: Cell division control protein 42 homolog, G25K GTP-binding protein
- ID gène
- 998
- NCBI Accession
- NP_001034891
- UniProt
- P60953
- Pathways
- Signalisation MAPK, Dynamique des Microtubules, Signalisation RTK, Signalisation WNT, TCR Signaling, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling
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