FREM2 anticorps (Center)

N° du produit ABIN783636

Détail du produit anti-FREM2 anticorps

Antigène: FREM2 (Fras1 Related Extracellular Matrix Protein 2 (FREM2))

Épitope: Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FREM2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts with Human and Mouse FREM2 and is predicted to not cross-react with other FRAS members. This antibody recognizes both isoforms of FREM2.

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid peptide near the center of Human FREM2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FREM2

Antigène: FREM2 (Fras1 Related Extracellular Matrix Protein 2 (FREM2))

Autre désignation: FREM2 (FREM2 Produits)

Synonymes: anticorps 6030440P17Rik, anticorps 8430406N05Rik, anticorps Gm409, anticorps b2b1562Clo, anticorps my, anticorps ne, anticorps nv1, anticorps RGD1566012, anticorps FRAS1 related extracellular matrix protein 2, anticorps Fras1 related extracellular matrix protein 2, anticorps FREM2, anticorps Frem2

Sujet: FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.Synonyms: ECM3 homolog, FRAS1-related extracellular matrix protein 2

ID gène: 341640

NCBI Accession: NP_997244

UniProt: Q5SZK8