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TRIM71 anticorps (C-Term)

TRIM71 Reactivité: Humain, Souris, Rat WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN783687
  • Antigène Voir toutes TRIM71 Anticorps
    TRIM71 (Tripartite Motif Containing 71, E3 Ubiquitin Protein Ligase (TRIM71))
    Épitope
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 16
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 15
    • 2
    Lapin
    Clonalité
    • 17
    Polyclonal
    Conjugué
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TRIM71 est non-conjugé
    Application
    • 8
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects TRIM71 at C-term.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    15 amino acid peptide near the carboxy terminus of human TRIM71
    Top Product
    Discover our top product TRIM71 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Antigène
    TRIM71 (Tripartite Motif Containing 71, E3 Ubiquitin Protein Ligase (TRIM71))
    Autre désignation
    TRIM71 (TRIM71 Produits)
    Synonymes
    anticorps LIN-41, anticorps LIN41, anticorps RGD1566388, anticorps 2610206G21Rik, anticorps AL022943, anticorps Gm1127, anticorps Lin41, anticorps Ripply2, anticorps lin-41, anticorps mLin41, anticorps mlin-41, anticorps tripartite motif containing 71, anticorps tripartite motif-containing 71, anticorps TRIM71, anticorps Trim71
    Sujet
    TRIM71 is the mammalian ortholog to the C. elegans heterochronic protein Lin41, a protein that is thought to be important in postembryonic development , and is genetically and biochemically downstream of both Shh and Fgf signaling pathways. Similar to its C. elegans homolog, TRIM71 is a target of the microRNA let-7 and is likely to play a role in mammalian development. Recent experiments have indicated that TRIM71 is an E3 ubiquitin ligase and can interact with the Dicer and the Argonaute proteins Ago1, Ago2, and Ago4. Overexpression and depletion of TRIM71 led to inverse changes in Ago2 protein levels, suggesting TRIM71 can regulate Ago2 turnover. Finally, TRIM71 cooperates with the pluripotency factor Lin-28 in regulating let-7.Synonyms: LIN41, Protein lin-41 homolog, Tripartite motif-containing protein 71
    ID gène
    131405
    NCBI Accession
    NP_001034200
    UniProt
    Q2Q1W2
    Pathways
    Tube Formation
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