NOD1 anticorps (C-Term)
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- Antigène Voir toutes NOD1 Anticorps
- NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
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Épitope
- C-Term
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NOD1 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects CARD4 / NOD1 at C-term.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- 16 amino acid peptide near the carboxy end of human NOD1
- Top Product
- Discover our top product NOD1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- Antigène
- NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
- Autre désignation
- CARD4 / NOD1 (NOD1 Produits)
- Synonymes
- anticorps CARD4, anticorps CLR7.1, anticorps NLRC1, anticorps C230079P11, anticorps Card4, anticorps F830007N14Rik, anticorps Nlrc1, anticorps RGD1562269, anticorps nucleotide binding oligomerization domain containing 1, anticorps nucleotide-binding oligomerization domain containing 1, anticorps NOD1, anticorps Nod1
- Sujet
- NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD1 contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and ten tandem leucine-rich repeats (LRRs) in its C-terminus. The CARD is involved in apoptotic signaling, and NOD1 activates caspase-9 and NF-kB. LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.Synonyms: Caspase recruitment domain-containing protein 4, Nucleotide-binding oligomerization domain-containing protein 1
- ID gène
- 10392
- NCBI Accession
- NP_006083
- UniProt
- Q9Y239
- Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Inflammasome
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