Cet anticorps anti-NLRC5 Polyclonal Lapin (ABIN783699) détecte spécifiquement NLRC5 dans WB, IF et EIA.
L’anticorps est réactif avec des échantillons de Humain et Souris.
NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-?B and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.Synonyms: CLR16.1, FLJ21709, FLJ39711, NLRC5, NOD27, NOD4