NALP8 anticorps (N-Term)

N° du produit ABIN783713

Détail du produit anti-NALP8 anticorps

Antigène: NALP8 (NLRP8) (NLR Family, Pyrin Domain Containing 8 (NLRP8))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NALP8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects NALP8 at N-term. This antibody is predicted to not cross-react with other NALP family members.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography purified via peptide column

Immunogène: 16 amino acid peptide near the amino terminus of Human NALP8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NALP8

Antigène: NALP8 (NLRP8) (NLR Family, Pyrin Domain Containing 8 (NLRP8))

Autre désignation: NALP8 (NLRP8 Produits)

Synonymes: anticorps CLR19.2, anticorps NALP8, anticorps NOD16, anticorps PAN4, anticorps NLR family pyrin domain containing 8, anticorps NLRP8

Sujet: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.Synonyms: LRR and PYD domains-containing protein 8, NACHT, NLRP8, NOD16, PAN4, PYRIN and NACHT-containing protein 4

ID gène: 126205

NCBI Accession: NP_789781

UniProt: Q86W28

Pathways: Inflammasome