NLRP11 anticorps (C-Term)

N° du produit ABIN783717

Détail du produit anti-NLRP11 anticorps

Antigène: NLRP11 (NLR Family, Pyrin Domain Containing 11 (NLRP11))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP11 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody will recognize all three isoforms of NALP2 and is predicted to not cross-react with other NALP family members.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity Chromatography purified via peptide column

Immunogène: 15 amino acid peptide near the carboxy terminus of Human NALP11

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NLRP11

Antigène: NLRP11 (NLR Family, Pyrin Domain Containing 11 (NLRP11))

Autre désignation: NALP11 (NLRP11 Produits)

Synonymes: anticorps CLR19.6, anticorps NALP11, anticorps NOD17, anticorps PAN10, anticorps PYPAF6, anticorps PYPAF7, anticorps NLR family pyrin domain containing 11, anticorps NLRP11

Sujet: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP11 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP11, it has been suggested that it has been associated with Crohn's disease.Synonyms: LRR and PYD domains-containing protein 11, NACHT, NLRP11, NOD17, Nucleotide-binding oligomerization domain protein 17, PYPAF6, PYRIN-containing APAF1-like protein 6

ID gène: 204801

NCBI Accession: NP_659444

UniProt: P59045

Pathways: Inflammasome