SYNPO2 anticorps (N-Term)

N° du produit ABIN783775

Détail du produit anti-SYNPO2 anticorps

Antigène: SYNPO2 (Synaptopodin 2 (SYNPO2))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYNPO2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects SYNPO2 at N-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 20 amino acid peptide near the amino terminus of human SYNPO2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur SYNPO2

Antigène: SYNPO2 (Synaptopodin 2 (SYNPO2))

Autre désignation: SYNPO2 (SYNPO2 Produits)

Synonymes: anticorps SYNOP2, anticorps RGD1564779, anticorps 1110069I04Rik, anticorps 2310068J10Rik, anticorps 9530006G20Rik, anticorps AI848603, anticorps Myo, anticorps synaptopodin 2, anticorps synaptopodin-2, anticorps SYNPO2, anticorps LOC100484043, anticorps Synpo2

Sujet: SYNPO2 was initially identified as myopodin, a member of the synaptopodin family that contains one PPXY motif and multiple PXXP motifs. It colocalizes with alpha-actinin and is found at the Z-disc and during stress conditions will translocate to the nucleus, suggesting that it is part of signaling pathways in addition to its function as a structural protein. SYNPO2 has been shown to bind to calmodulin, alpha-actinin, and smooth muscle myosin and will stimulate actin polymerization in a calmodulin dependent manner, consistent with its proposed role in organizing the cytoskeleton. While deletion of SYNPO2 has been reported to be highly correlated with the invasiveness of prostate cancers, other reports suggest that down-regulation of SYNPO2 reduces the invasiveness and motility of prostate cancer cells.

ID gène: 171024

NCBI Accession: NP_001122405

UniProt: Q9UMS6