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TMEM59 anticorps (N-Term)
TMEM59
Reactivité: Humain
WB, EIA
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-TMEM59 anticorps
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Antigène
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TMEM59
(Transmembrane Protein 59 (TMEM59))
Épitope
Tous les épitopes à travers TMEM59 Anticorps.
N-Term
Reactivité
Toutes les réactivités sur TMEM59 Anticorps
Humain
Hôte
Toutes les hôtes sur TMEM59 Anticorps
Lapin
Clonalité
Toutes les clonalités sur TMEM59 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers TMEM59 Anticorps
Cet anticorp TMEM59 est non-conjugé
Application
Tous les applications à travers TMEM59 Anticorps.
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificité
This antibody detects TMEM59 at N-term.
Réactivité croisée (Details)
Species reactivity (tested):Human
Purification
Affinity chromatography purified via peptide column
Immunogène
16 amino acid peptide near amino terminus of human TMEM59
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Buffer
PBS containing 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Détails sur TMEM59
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Antigène
TMEM59
(Transmembrane Protein 59 (TMEM59))
Autre désignation
TMEM59 (TMEM59 Produits )
Synonymes
anticorps Tmem59, anticorps C1orf8, anticorps HSPC001, anticorps 1110001M20Rik, anticorps 3110046P06Rik, anticorps AI256529, anticorps D4Ertd20e, anticorps MTDCF1, anticorps ORF18, anticorps transmembrane protein 59, anticorps tmem59, anticorps Tmem59, anticorps TMEM59
Sujet
Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.Synonyms: C1orf8, HSPC001, Liver membrane-bound protein, Transmembrane protein 59
ID gène
9528
NCBI Accession
NP_004863
UniProt
Q9BXS4
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