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PDGFRA anticorps (AA 1035-1053)
PDGFRA
Reactivité: Humain, Souris, Rat, Poulet, Xenopus laevis
WB, IHC (p), IP
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-PDGFRA anticorps
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Antigène
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PDGFRA
(Platelet Derived Growth Factor Receptor alpha (PDGFRA))
Épitope
Tous les épitopes à travers PDGFRA Anticorps.
AA 1035-1053
Reactivité
Toutes les réactivités sur PDGFRA Anticorps
Humain, Souris, Rat, Poulet, Xenopus laevis
Hôte
Toutes les hôtes sur PDGFRA Anticorps
Lapin
Clonalité
Toutes les clonalités sur PDGFRA Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers PDGFRA Anticorps
Cet anticorp PDGFRA est non-conjugé
Application
Tous les applications à travers PDGFRA Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
Séquence
C-GKRNRHSSQT SEESAIETG Remarks: Antigen Modificati on: Amino acids 1035-1053
Specificité
Recognizes Human PDGF Receptor Type A, doublet, Mr 150/170 kDa.
Réactivité croisée (Details)
Species reactivity (expected):Chicken, Frog, Mouse, Rat, Zebrafish. Species reactivity (tested):Human.
Purification
Immunoaffinity Chromatography
Immunogène
Synthetic peptide KLH-conjugated corresponding to amino acids 1035-1053 of Human PDGF.
Isotype
IgG
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
0.2 M Tris-Glycine, pH 7.4 containing 0.12 M Sodium Chloride and 0.05 % Sodium Azide as preservative
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze-thaw cycles.
Détails sur PDGFRA
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Antigène
PDGFRA
(Platelet Derived Growth Factor Receptor alpha (PDGFRA))
Autre désignation
CD140a / PDGFRA (PDGFRA Produits )
Synonymes
anticorps AI115593, anticorps CD140a, anticorps Pdgfr-2, anticorps APDGFR, anticorps PDGFACE, anticorps CD140A, anticorps PDGFR-2, anticorps PDGFR2, anticorps RHEPDGFRA, anticorps PDGFR, anticorps PDGFR-A, anticorps platelet derived growth factor receptor alpha, anticorps platelet derived growth factor receptor, alpha polypeptide, anticorps platelet-derived growth factor receptor, alpha polypeptide L homeolog, anticorps platelet-derived growth factor receptor, alpha polypeptide, anticorps PDGFRA, anticorps Pdgfra, anticorps pdgfra.L
Sujet
Platelet-derived Growth Factor Receptor Alpha (PDGFR alpha), a member of the a PDGF Receptor tyrosine kinase family, is a mediator of the biological actions of platelet-derived growth factor (PDGF). PDGF binding to PDGF receptors result in stimulation of cell growth, chemotaxis, and cell shape changes. Unlike PDGFR beta, PDGFR alpha can bind to both PDGF subunits. PDGFR alpha has been implicated in the development of spina bifida. In various mouse models, deregulated PDGFR alpha expression was found to result in congenital neural tube defects. In humans, various PDGFRA promoter haplotypes have been associated with neural tube defects.Synonyms: Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, PDGF Receptor alpha, PDGF-R-alpha
ID gène
5156
NCBI Accession
NP_006197
Pathways
Signalisation RTK , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Platelet-derived growth Factor Receptor Signaling
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