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Clvs1/2 anticorps (C-Term)

Clvs1/2 Reactivité: Humain, Souris, Rat IF, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN784598
  • Antigène
    Clvs1/2 (Clavesin 1/2 (Clvs1/2))
    Épitope
    C-Term
    Reactivité
    Humain, Souris, Rat
    Hôte
    Lapin
    Clonalité
    Polyclonal
    Application
    Immunofluorescence (IF), Western Blotting (WB)
    Specificité
    Specific for the ~35 kDa Clavesin 1/2 protein doublet in Western blots of Rat brain lysate. Isoform-specific knock down in cultured hippocampal neurons indicates that the lower and upper bands are Clavesin 1 and 2, respectively.
    Réactivité croisée (Details)
    Species reactivity (expected):Human and Mouse.
    Species reactivity (tested):Rat.
    Purification
    Affinity Chromatography.
    Immunogène
    Synthetic peptide KLH-conjugated corresponding to amino acid residues from the C-terminal region of Rat Clavesin-1. Genename: CLVS1/2
    Isotype
    IgG
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS containing 50 % Glycerol.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody undiluted (in aliquots) at -20 °C.
  • Antigène
    Clvs1/2 (Clavesin 1/2 (Clvs1/2))
    Sujet
    Clavesin (clathrin vesicle associated Sec14 protein) is a novel neuron specific protein that has recently been identified and shown to be required for normal morphology of late endosomes and/or lysosomes as lentiviral-mediated knockdown of clavesin in hippocampal neurons causes lysosomal defects (Katoh et al., 2009). Additionally, upregulation of clavesin in human hepatocellular carcinoma has recently been demonstrated thus making it a useful marker for this disease state (Zhao et al., 2008).Synonyms: C6orf212, C6orf213, CLVS1, CLVS2, CRALBPL, Cellular retinaldehyde-binding protein-like, RLBP1L1, RLBP1L2, Retinaldehyde-binding protein 1-like 1/2
    ID gène
    366311
    NCBI Accession
    NP_001102439
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