ERBB4 anticorps (pTyr1188) (HRP)
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- Antigène Voir toutes ERBB4 Anticorps
- ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))
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Épitope
- pTyr1188
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ERBB4 est conjugé à/à la HRP
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Souris
- Homologie
- Human,Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic phosphopeptide derived from human HER4 around the phosphorylation site of Tyr1188
- Isotype
- IgG
- Top Product
- Discover our top product ERBB4 Anticorps primaire
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- Indications d'application
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IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))
- Autre désignation
- HER4 (ERBB4 Produits)
- Synonymes
- anticorps erbb4, anticorps si:ch211-227n20.1, anticorps Her4, anticorps c-erbB-4, anticorps HER4, anticorps p180erbB4, anticorps erb-b2 receptor tyrosine kinase 4, anticorps erb-b2 receptor tyrosine kinase 4a, anticorps v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian), anticorps erb-b2 receptor tyrosine kinase 4 L homeolog, anticorps receptor tyrosine-protein kinase ErbB-4, anticorps ERBB4, anticorps erbb4a, anticorps erbb4, anticorps erbb4.L, anticorps Tsp_13582, anticorps Erbb4
- Sujet
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Synonyms: ErbB 4 phospho Y1188, p-ErbB 4 phospho Y1188, ErbB4, HER 4, HER4, Avian erythroblastic leukemia viral oncogene homolog 4, Avian erythroblastic leukemia viral v erb b2 oncogene homolog 4, MGC138404, P180erbB4, Receptor protein tyrosine kinase erbB 4 precursor, Receptor tyrosine protein kinase erbB 4,Tyrosine kinase type cell surface receptor HER4, v erb a avian erythroblastic leukemia viral oncogene homolog like 4, v erb a erythroblastic leukemia viral oncogene homolog 4, Verba avian erythroblastic leukemia viral oncogene homolog like 4, Verba erythroblastic leukemia viral oncogene homolog 4, VERBB2.
Background: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].
- ID gène
- 2066
- Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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