G3BP1 anticorps (pSer232)

N° du produit ABIN801153

Détail du produit anti-G3BP1 anticorps

Antigène: G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

Épitope: pSer232

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp G3BP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human G3BP1 around the phosphorylation site of Ser232

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-G3BP1 (ABIN801153)

Luo, Fang, Jin, Wang, An, Xu, Chen, Xiao: "Label-free quantitative phosphoproteomic analysis reveals differentially regulated proteins and pathway in PRRSV-infected pulmonary alveolar macrophages." dans: Journal of proteome research, Vol. 13, Issue 3, pp. 1270-80, (2014) (PubMed).

Détails sur G3BP1

Antigène: G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

Autre désignation: G3BP1 (G3BP1 Produits)

Synonymes: anticorps G3BP, anticorps HDH-VIII, anticorps fj17h05, anticorps zgc:56034, anticorps wu:fj17h05, anticorps g3bp, anticorps MGC53271, anticorps G3BP1, anticorps G3bp, anticorps RGD1310666, anticorps AI849976, anticorps B430204O07, anticorps C87777, anticorps mKIAA4115, anticorps G3BP stress granule assembly factor 1, anticorps GTPase activating protein (SH3 domain) binding protein 1, anticorps GTPase activating protein (SH3 domain) binding protein 1 L homeolog, anticorps Ras-GTPase-activating protein SH3-domain-binding protein, anticorps G3BP1, anticorps g3bp1, anticorps g3bp1.L, anticorps LOC100304885, anticorps G3bp1

Sujet:

Synonyms: G3BP, HDH-VIII, Ras GTPase-activating protein-binding protein 1, G3BP-1, ATP-dependent DNA helicase VIII, hDH VIII, GAP SH3 domain-binding protein 1, G3BP1

Background: May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.

ID gène: 10146

UniProt: Q13283

Pathways: SARS-CoV-2 Protein Interactome