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PLCz1 anticorps (AA 351-450)

PLCz1 Reactivité: Rat ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN801183
  • Antigène Voir toutes PLCz1 Anticorps
    PLCz1 (Phospholipase C zeta 1 (PLCz1))
    Épitope
    • 14
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reactivité
    • 20
    • 14
    • 4
    Rat
    Hôte
    • 33
    • 2
    Lapin
    Clonalité
    • 33
    • 2
    Polyclonal
    Conjugué
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PLCz1 est non-conjugé
    Application
    • 12
    • 12
    • 11
    • 10
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PLCZ1
    Isotype
    IgG
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    PLCz1 (Phospholipase C zeta 1 (PLCz1))
    Autre désignation
    PLCZ1 (PLCz1 Produits)
    Synonymes
    anticorps PLC-zeta-1, anticorps PLCZ1, anticorps 1700041H07Rik, anticorps PLCzeta, anticorps NYD-SP27, anticorps PLCZ, anticorps phospholipase C zeta 1, anticorps phospholipase C, zeta 1, anticorps PLCZ1, anticorps Plcz1
    Sujet

    Synonyms: PLCzeta, NYD-SP27, PLC-zeta-1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1, Phosphoinositide phospholipase C-zeta-1, Phospholipase C-zeta-1, Testis-development protein NYD-SP27, PLCZ1, PLCZ1_HUMAN

    Background: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.

    ID gène
    89869
    UniProt
    Q86YW0
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