IRS2 anticorps (pSer731)
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- Antigène Voir toutes IRS2 Anticorps
- IRS2 (Insulin Receptor Substrate 2 (IRS2))
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Épitope
- pSer731
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IRS2 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic phosphopeptide derived from human IRS-2 around the phosphorylation site of Ser731
- Isotype
- IgG
- Top Product
- Discover our top product IRS2 Anticorps primaire
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- Indications d'application
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WB: (1:100-1000), IHC-P: (1:100-500), IF(IHC-P): (1:50-200)
Optimal working dilution should be determined by the investigator. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- IRS2 (Insulin Receptor Substrate 2 (IRS2))
- Autre désignation
- Irs-2 (IRS2 Produits)
- Synonymes
- anticorps IRS2, anticorps si:dkeyp-24d6.1, anticorps IRS-2, anticorps 4PS, anticorps Irs-2, anticorps insulin receptor substrate 2, anticorps insulin receptor substrate 2a, anticorps insulin receptor substrate 2b, anticorps IRS2, anticorps irs2a, anticorps irs2b, anticorps Irs2
- Sujet
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Synonyms: Insulin Receptor Substrate 2, IRS 2, IRS2.
Background: The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions, however, the distinct physiological roles of each IRS are unclear. Summary: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
- ID gène
- 8660
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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