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TAB1 anticorps (AA 601-712)

TAB1 Reactivité: Souris, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN801873
  • Antigène Voir toutes TAB1 Anticorps
    TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
    Épitope
    • 15
    • 14
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 601-712
    Reactivité
    • 94
    • 40
    • 28
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Souris, Rat
    Hôte
    • 96
    • 10
    • 2
    Lapin
    Clonalité
    • 99
    • 9
    Polyclonal
    Conjugué
    • 41
    • 9
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp TAB1 est non-conjugé
    Application
    • 71
    • 45
    • 25
    • 25
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human TAB3
    Isotype
    IgG
    Top Product
    Discover our top product TAB1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Hussain, Zhao, Shah, Wang, Yue, Liao, Sabir, Yang, Zhou et al.: "MicroRNA 27a-3p Regulates Antimicrobial Responses of Murine Macrophages Infected by Mycobacterium avium subspecies paratuberculosis by Targeting Interleukin-10 and TGF-β-Activated Protein Kinase 1 ..." dans: Frontiers in immunology, Vol. 8, pp. 1915, (2017) (PubMed).

  • Antigène
    TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
    Autre désignation
    TAB1 (TAB1 Produits)
    Synonymes
    anticorps 3'-Tab1, anticorps MAP3K7IP1, anticorps 2310012M03Rik, anticorps Map3k7ip1, anticorps b2b449Clo, anticorps TGF-beta activated kinase 1 (MAP3K7) binding protein 1, anticorps TGF-beta activated kinase 1/MAP3K7 binding protein 1, anticorps TAB1, anticorps Tab1
    Sujet

    Synonyms: MAP3K7IP 3, Mitogen activated protein kinase kinase kinase 7 interacting protein 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, NAP1, NF kappa B activating protein 1, NF-kappa-B-activating protein 1, NFkB activating protein 1, TAB-3, TAB3, TAB3_HUMAN, TAK1 binding protein 3, TAK1-binding protein 3, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, TGF-beta-activated kinase 1-binding protein 3.

    Background: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

    ID gène
    257397
    UniProt
    Q8N5C8
    Pathways
    Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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