DUX4 anticorps (C-Term)
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- Antigène Voir toutes DUX4 Anticorps
- DUX4 (Double Homeobox 4 (DUX4))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp DUX4 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- Detects ~45 kDa. No cross-reactivity with DUX4c.
- Réactivité croisée
- Humain, Souris
- Purification
- Protein G Purified
- Immunogène
- C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag
- Clone
- P2B1
- Isotype
- IgG1
- Top Product
- Discover our top product DUX4 Anticorps primaire
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- Indications d'application
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- WB (1:1000)
- ICC/IF (1:1000)
- optimal dilutions for assays should be determined by the user.
- Commentaires
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1 μg/ml of ABIN863109 was sufficient for detection of DUX4 in 20 μg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C
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- Antigène
- DUX4 (Double Homeobox 4 (DUX4))
- Autre désignation
- DUX4 (DUX4 Produits)
- Synonymes
- anticorps DUX4, anticorps DUX4L, anticorps double homeobox, 4, anticorps double homeobox 4, anticorps DUX4
- Sujet
- DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1 (1). Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues (5).
- ID gène
- 22947
- NCBI Accession
- NP_149418
- UniProt
- F5GZ66
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