MDC1 anticorps (N-Term)
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- Antigène Voir toutes MDC1 Anticorps
- MDC1 (Mdc1 (MDC1))
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Épitope
- N-Term
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Reactivité
- Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MDC1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- Detects ~184 kDa. This antibody recognizes MDC1 at and around the N-terminus.
- Réactivité croisée
- Chimpanzé, Boeuf (Vache), Humain, Souris
- Purification
- Protein G Purified
- Immunogène
- GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus
- Clone
- P2B11
- Isotype
- IgG1
- Top Product
- Discover our top product MDC1 Anticorps primaire
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- Indications d'application
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- WB (1:2000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Commentaires
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0.5 μg/ml of ABIN863114 was sufficient for detection of MDC1 in 10 μg of HeLa cell lysate by ECL immunoblot analysis.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C
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- Antigène
- MDC1 (Mdc1 (MDC1))
- Autre désignation
- MDC1 (MDC1 Produits)
- Synonymes
- anticorps 6820401C03, anticorps AA413496, anticorps Nfbd1, anticorps mKIAA0170, anticorps NFBD1, anticorps mediator of DNA damage checkpoint 1, anticorps mediator of DNA-damage checkpoint 1, anticorps Mdc1, anticorps MDC1
- Sujet
- MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.
- ID gène
- 240087
- NCBI Accession
- NP_001010833
- UniProt
- Q5PSV9
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