HDAC8 anticorps (pSer39)
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- Antigène Voir toutes HDAC8 Anticorps
- HDAC8 (Histone Deacetylase 8 (HDAC8))
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Épitope
- pSer39
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HDAC8 est non-conjugé
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Specificité
- The antibody detects endogenous level of HDAC8 only when phosphorylated at serine 39.
- Purification
- Affinity purified
- Immunogène
- Peptide sequence around phosphorylation site of pSer39 (R-A-S (p) -M-V) derived from Human HDAC8. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Top Product
- Discover our top product HDAC8 Anticorps primaire
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- Indications d'application
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Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Antigène
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- Autre désignation
- HDAC8 (HDAC8 Produits)
- Synonymes
- anticorps HD8, anticorps CDLS5, anticorps HDACL1, anticorps MRXS6, anticorps RPD3, anticorps WTS, anticorps 2610007D20Rik, anticorps RGD1562895, anticorps wu:fd19a02, anticorps zgc:66196, anticorps ATHDA8, anticorps HDA8, anticorps HISTONE DEACETYLASE 8, anticorps T27G7.14, anticorps T27G7_14, anticorps histone deacetylase 8, anticorps histone deacetylase 8, anticorps histone deacetylase 8 L homeolog, anticorps CC1G_05302, anticorps hdac8, anticorps HDAC8, anticorps Hdac8, anticorps hdac8.L, anticorps HDA08
- Sujet
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
- 42 kDa
- ID gène
- 558
- NCBI Accession
- NP_001159
- UniProt
- Q9BY41
- Pathways
- Cellular Glucan Metabolic Process
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