×
Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.
c-MYC anticorps (C-Term)
MYC
Reactivité: Humain
WB
Hôte: Souris
Monoclonal
unconjugated
Détail du produit anti-c-MYC anticorps
(cache)
Antigène
Voir toutes c-MYC (MYC) Anticorps
c-MYC (MYC)
(Myc Proto-Oncogene protein (MYC))
Épitope
Tous les épitopes à travers c-MYC Anticorps.
AA 410-432, C-Term
Reactivité
Toutes les réactivités sur c-MYC Anticorps
Humain
Hôte
Toutes les hôtes sur c-MYC Anticorps
Souris
Clonalité
Toutes les clonalités sur c-MYC Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers c-MYC Anticorps
Cet anticorp c-MYC est non-conjugé
Application
Tous les applications à travers c-MYC Anticorps.
Western Blotting (WB)
Specificité
This mouse mAb only detects transfected proteins.
Purification
Affinity purified
Immunogène
Peptide sequence derived from C-terminal (AA 410-432) of human c-Myc conjugated with KLH.
Top Product
Discover our top product MYC Anticorps primaire
Alternatives
(show)
Information d'application
(cache)
Indications d'application
Western blotting: 1:500-1:1000
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Conseil sur la manipulation
Avoid freezing and thawing repeatly.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C for short term use. Store at -20 °C for long term preservation. Avoid freezing and thawing repeatly.
Références pour anticorps anti-c-MYC (ABIN871460)
(cache)
Yang, Xia, Hawke, Li, Liang, Xing, Aldape, Hunter, Alfred Yung, Lu : "PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis. " dans: Cell , Vol. 150 , Issue 4 , pp. 685-96 , (2012 ) (PubMed ).
Yang, Zheng, Xia, Ji, Chen, Guo, Lyssiotis, Aldape, Cantley, Lu : "ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect. " dans: Nature cell biology , Vol. 14 , Issue 12 , pp. 1295-304 , (2012 ) (PubMed ).
Détails sur c-MYC
(cache)
Antigène
c-MYC (MYC)
(Myc Proto-Oncogene protein (MYC))
Autre désignation
Myc Proto-Oncogene protein (MYC Produits )
Synonymes
anticorps MRTL, anticorps MYCC, anticorps bHLHe39, anticorps c-Myc, anticorps CMYC, anticorps c-myc, anticorps C-MYC, anticorps LOC100136746, anticorps ARC, anticorps B430311C09Rik, anticorps MYC, anticorps NOP, anticorps Nop30, anticorps RNCMYC, anticorps mMyc, anticorps AU016757, anticorps Myc2, anticorps Niard, anticorps Nird, anticorps cmyc, anticorps zc-myc, anticorps c-myc II, anticorps myc-B, anticorps myc2, anticorps myc1, anticorps CMyc, anticorps zgc:55680, anticorps CG10798, anticorps D-Myc, anticorps DM, anticorps DMYc, anticorps Dm, anticorps Dmel\CG10798, anticorps Dmyc, anticorps EG:BACN5I9.1, anticorps anon-WO03040301.171, anticorps bHLHe57, anticorps c-MYC, anticorps d-myc, anticorps dMYC, anticorps dMyc, anticorps dMyc1, anticorps da, anticorps dm, anticorps dm/dMyc, anticorps dm/myc, anticorps dmyc, anticorps dmyc1, anticorps l(1)G0139, anticorps l(1)G0354, anticorps l(1)G0359, anticorps myc, anticorps MYC proto-oncogene, bHLH transcription factor, anticorps v-myc myelocytomatosis viral oncogene homolog, anticorps nucleolar protein 3 (apoptosis repressor with CARD domain), anticorps myelocytomatosis oncogene, anticorps MYC proto-oncogene, bHLH transcription factor a, anticorps MYC proto-oncogene, bHLH transcription factor L homeolog, anticorps MYC proto-oncogene, bHLH transcription factor S homeolog, anticorps v-myc myelocytomatosis viral oncogene homolog (avian), anticorps MYC proto-oncogene, bHLH transcription factor b, anticorps CG10798 gene product from transcript CG10798-RB, anticorps MYC, anticorps LOC100136746, anticorps Nol3, anticorps Myc, anticorps myca, anticorps myc.L, anticorps myc.S, anticorps mycb
Sujet
Myc proto-oncogene encodes nuclear DNA-binding phosphoproteins that are involved in the regulation of gene expression and DNA replication during cell growth and differentiation. Myc encodes a protein of 65 kDa which is expressed in almost all normal and transformed cells. The expression correlates with the proliferation state of the cells. Transcription is repressed in quiescent or terminally differentiated cells. Expression of Myc is generally induced after mitogenic stimulation of cells or serum induction. Myc therefore is an important positive regulator of cell growth and proliferation. Myc has been demonstrated also to be a potent inducer of apoptosis when expressed in the absence of serum or growth factors. Apoptosis may serve also as a protective mechanism to prevent tumorigenicity elicited by deregulated Myc expression. Sequences of the Myc oncogene have been highly conserved throughout evolution, from Drosophila to vertebrates
Poids moléculaire
60 kDa
ID gène
4609
NCBI Accession
NP_002458
UniProt
P01106
Pathways
Signalisation p53 , Cycle Cellulaire , Sensory Perception of Sound , Transition Metal Ion Homeostasis , Mitotic G1-G1/S Phases , Positive Regulation of Endopeptidase Activity , Regulation of Carbohydrate Metabolic Process , Positive Regulation of Response to DNA Damage Stimulus , L'effet Warburg
Vus récemment
(cache)