PPARGC1B anticorps (AA 901-1023)
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- Antigène Voir toutes PPARGC1B Anticorps
- PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))
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Épitope
- AA 901-1023
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PPARGC1B est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Pig,Rabbit,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human PGC1 beta
- Isotype
- IgG
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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Down-regulating peroxisome proliferator-activated receptor-gamma coactivator-1 beta alleviates the proinflammatory effect of rheumatoid arthritis fibroblast-like synoviocytes through inhibiting ..." dans: Arthritis research & therapy, Vol. 16, Issue 5, pp. 472, (2015) (PubMed).
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Down-regulating peroxisome proliferator-activated receptor-gamma coactivator-1 beta alleviates the proinflammatory effect of rheumatoid arthritis fibroblast-like synoviocytes through inhibiting ..." dans: Arthritis research & therapy, Vol. 16, Issue 5, pp. 472, (2015) (PubMed).
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- Antigène
- PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))
- Autre désignation
- PGC1 beta (PPARGC1B Produits)
- Synonymes
- anticorps PPARGC1B, anticorps 4631412G21Rik, anticorps Perc, anticorps PGC1beta, anticorps ERRL1, anticorps PERC, anticorps PGC-1(beta), anticorps PGC1B, anticorps PPARG coactivator 1 beta, anticorps peroxisome proliferative activated receptor, gamma, coactivator 1 beta, anticorps PPARGC1B, anticorps Ppargc1b
- Sujet
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Synonyms: PERC, peroxisome prolerative activated receptor, gamma, coactivator 1, peroxisome prolerator-activated receptor gamma coactivator 1 beta, Peroxisome prolerator-activated receptor gamma coactivator 1-beta, peroxisome prolerator-activated receptor gamma, coactivator 1 beta, PGC-1beta, PGC-1-beta, PGC-1-related estrogen receptor alpha coactivator, PGC1, PPAR gamma coactivator-1beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta, PPARGC1, Ppargc1b, PRGC2_HUMAN.
Background: Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure.Tissue specificity: Ubiquitous with higher expression in heart, brain and skeletal muscle.
- Poids moléculaire
- 113kDa
- ID gène
- 133522
- Pathways
- AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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