KDM4A anticorps (AA 75-155)
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- Antigène Voir toutes KDM4A Anticorps
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
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Épitope
- AA 75-155
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KDM4A est non-conjugé
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Souris
- Homologie
- Human,Rat,Dog,Cow,Sheep,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human JMJD2A/KDM4A
- Isotype
- IgG
- Top Product
- Discover our top product KDM4A Anticorps primaire
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- Indications d'application
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
- Autre désignation
- JMJD2A (KDM4A Produits)
- Synonymes
- anticorps JMJD2A, anticorps JHDM3A, anticorps JMJD2, anticorps TDRD14A, anticorps D4Ertd222e, anticorps Jmjd2, anticorps Jmjd2a, anticorps mKIAA0677, anticorps lysine demethylase 4A, anticorps lysine-specific demethylase 4A, anticorps lysine (K)-specific demethylase 4A, anticorps KDM4A, anticorps LOC100228023, anticorps Kdm4a
- Sujet
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Synonyms: JMJ2A, JmjC domain containing histone demethylation protein 3A, JmjC domain-containing histone demethylation protein 3A, JMJD2, jumonji C domain containing histone demethylase 3A, Jumonji domain containing 2, Jumonji domain containing 2A, Jumonji domain containing protein 2A, Jumonji domain-containing protein 2A, KDM4A, KDM2A_HUMAN, KIAA0677, Lysine-specic demethylase 4A.
Background: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
- Pathways
- L'effet Warburg
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