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Nidogen anticorps (AA 1001-1100)

NID Reactivité: Souris, Rat ELISA, IF (cc), IF (p), IHC (fro), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN872401
  • Antigène Tous les produits Nidogen (NID)
    Nidogen (NID)
    Épitope
    • 2
    • 1
    • 1
    AA 1001-1100
    Reactivité
    • 11
    • 2
    • 2
    Souris, Rat
    Hôte
    • 10
    • 1
    Lapin
    Clonalité
    • 10
    • 1
    Polyclonal
    Conjugué
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Nidogen est non-conjugé
    Application
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Cow,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Entactin
    Isotype
    IgG
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Nidogen (NID)
    Autre désignation
    Nidogen (NID Produits)
    Synonymes
    anticorps BEST:CK00552, anticorps CG12908, anticorps CT32053, anticorps Dmel\\CG12908, anticorps ndg, anticorps Nidogen/entactin, anticorps Ndg
    Sujet

    Synonyms: Ent, Entactin 1, Entactin, NID 1, NID, NID-1, Nid1, NID1_HUMAN, Nidogen enactin, Nidogen 1, Nidogen, Nidogen-1, NID1_HUMAN.

    Background: Basement membranes are the earliest extracellular matrices produced during embryogenesis. They are synthesized and incorporated into the supramolecular architecture of several components, including laminins, Collagen IV, Nidogen and proteoglycans. Nidogen/Entactin, a sulfated glycoprotein, acts as a link between the extracellular matrix molecules Laminin 1 and Collagen Type IV, and thereby participates in the assembly of basement membranes. Nidogen is a highly conserved member of the Nidogen family, which also includes Nidogen-2. Nidogen-2 has a high level of N- and O-glycosylation, and it interacts with Collagens Type I and IV and Perlecan at a comparable level to Nidogen. Nidogen is synthesized and secreted in primary and established mesenchymal peritubular cells and myoepithelial cells, and it affects adhesion of peritubular cells in an autocrine manner. Nidogen is expressed during embryonic and fetal development exclusively in fully developed basement membranes of the ectoderm and is not expressed in the developing endodermal basement membrane or in membranes disrupted during mesoderm formation. Nidogen also cooperates with Laminin 1 to regulate b-casein expression.

    ID gène
    4811
    UniProt
    P14543
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