CEND1 anticorps (AA 4-100)
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- Antigène Voir toutes CEND1 Anticorps
- CEND1 (Cell Cycle Exit and Neuronal Differentiation 1 (CEND1))
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Épitope
- AA 4-100
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Reactivité
- Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CEND1 est non-conjugé
- Application
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Souris, Rat
- Homologie
- Human,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human CEND1
- Isotype
- IgG
- Top Product
- Discover our top product CEND1 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CEND1 (Cell Cycle Exit and Neuronal Differentiation 1 (CEND1))
- Autre désignation
- CEND1 (CEND1 Produits)
- Synonymes
- anticorps BM88, anticorps 1500001H12Rik, anticorps AI415214, anticorps C38, anticorps RGD1309401, anticorps cell cycle exit and neuronal differentiation 1, anticorps CEND1, anticorps Cend1
- Sujet
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Synonyms: BM88, BM88 antigen, Cell cycle exit and neuronal dferentiation 1, Cell cycle exit and neuronal dferentiation protein 1, FLJ90066, MGC34326, CEND_HUMAN
Background: BM88 is a 149 amino acid protein that belongs to the CEND1 familly. Involved in neuroblastoma cell differentiation, BM88 is a single-pass type IV membrane protein that is neuron specific. It is suggested that BM88 forms a dimer of two identical polypeptides linked by disulfide bridges. BM88 has a central proline-rich region containing four PxxP motifs, which typically bind SRC homology-3 (SH3) domains, as well as a putative C-terminal transmembrane region, and several potential sites for N-glycosylation, myristoylation and phosphorylation. It is also suggested that a novel signaling mechanism exists by which BM88 interferes with calcium release from inositol 1,4,5-trisphosphate-sensitive stores and exerts anti-proliferative and anti-apoptotic functions. BM88 is an important molecular target for HDAC inhibition, and transcription of BM88 is induced by trichostatin-A.
- ID gène
- 51286
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